Making Aggregation-Induced Emission Luminogen More Valuable by Gold: Enhancing Anticancer Efficacy by Suppressing Thioredoxin Reductase Activity

Gold complexes have been acknowledged as potential anticancer brokers towards numerous sorts of illnesses attributable to their inherent suppressions of antioxidant thioredoxin reductase (TrxR) exercise. Herein, a strong aggregation-induced emission luminogen (AIEgen), TBP-Au, was designed and synthesized by integrating an anticancer Au(I) moiety with an AIE-active photosensitizer (TBP), by which each the manufacturing and consumption … Read more