Ferroptosis/pyroptosis dual-inductive combinational anti-cancer therapy achieved by transferrin decorated nanoMOF

Non-apoptotic cell dying resembling ferroptosis and pyroptosis has shed new gentle on most cancers remedy, whereas combinational remedy utilizing each these mechanisms has not but been absolutely explored. Herein, a dual-inductive nano-system to comprehend ferroptosis/pyroptosis mediated anti-cancer results is introduced. The nanodrug (Tf-LipoMof@PL) is constructed with a piperlongumine (PL) loaded metallic–natural framework (MOF) coated with … Read more